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You Ask. We Answer.

What is CBD?

CBD is an abbreviation for Cannabidiol which is a chemical compound that comes from the Cannabid Sativa Plant better known as a marijuana plant. CBD is the most prominent and promising component found in marijuana. THC may ring bells when heard, CBD is just the second most prevalent non-psychoactive part of the plant. CBD occurs naturally and is used in many products, from edibles to oils.

How Does CBD work in the body?

CBD activates multiple receptors and ion channels. CBD inhibits the reuptake of endogenous neurotransmitters that THC would normally act on. Furthermore, CBD inhibits or enhances the binding of certain G-protein coupled receptors. CBD acts as both a positive and negative allosteric modulator. In which case, CBD is a positive allosteric modulator when it amplifies the body's ability to transmit GABA (gamma aminobutyric acid) which is the main inhibitory neurotransmitter in the Central Nervous System. In turn CBD acts as a negative allosteric modulator of the CB1 receptor to reduce the psychoactive affects caused by THC. This helps direct the body in how to perceive pain and inflammation, response to dealing with anxiety as well as influence balance. CBD creates a feeling of calm and influences relaxation because CBD reacts with receptors in the nervous system to mellow and keep one from being in a heightened fight or flight response.

Benefits of CBD?

CBD is a naturally occurring substance that comes with many benefits some of which are putting CBD at a more popular demand. Strongest scientific evidence points to CBD’s aid in severe cases of childhood epilepsy. The more common benefit of CBD is its aid in anxiety, depression and other related symptoms. Other popular demands for CBD are insomnia, and in study CBD can not only help with falling sleep but staying asleep. CBD can also be used to treat some chronic pain and modulates inflammation. CBD activates PPAR’s (peroxisome proliferator activated receptors) on cancerous cells which has an affect that often induces tumor regression. As the effect of CBD is studied in how it acts on PPAR’s it may open the door to development of treatments dealing with Alzheimer’s disease, diabetes and other possible functions.

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About Us

For the Community By the Community

We took a leap of faith with starting our company in the middle of a pandemic, a better time than any because in a time where everything seems chaotic CBD based products are in huge demand for relief and relaxation. Driven by our interest in the global hemp industry we took action with the establishment of our very own company. Despite the 2020 establishment we have been in this industry for over a decade! Here at Mary Jane And Company we strive to do something different, and so in building this company we want to build our community’s knowledge with health and awareness. We work with reputable manufacturers that operate in certified, inspected facilities to provide top quality all natural organic products. By doing this we offer healthy alternatives to everyone! We seek to set a very high standard in the industry by offering a full-spectrum distillate in all of our products. Touching people’s lives through education and understanding matters more than anything! Through our journey and with our strong mission our goal is to provide options that not only help with your health and healing but that will create a safe, relaxing, yet energizing experience. This company is the true meaning of for the community by the community.

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Important Information

We ask that all products be used responsibly. Products affect everyone differently. Do not drive or operate any machinery while using products with higher potency because there may be stronger effects. Consult your physician before using certain products. Do not use if pregnant, nursing, or if you have diagnosed or undiagnosed health conditions. We do not condone the purchase or use of our products by minors under the age of 21.

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Mary Jane and Company Policies

At Mary Jane and Company, we want to give our customers the best shopping experience. That’s why we believe our store policies should be fair, clear, and transparent. Read about them below, and contact us with questions.

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Contact Us

For quick assistance questions can be submitted using the contact form!

8559 Airport Rd
Saint Louis, Missouri 63134

Call Us at 314-733-5345

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Hours of Operation

*Limited capacity
*Masks are mandatory

Mon - Fri: 10am - 7pm
Sat: 10am - 5pm
Sun: Closed

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